Representative results of RAD51 protein expression by immunohistochemical analysis.

<p>Percentage of positive cells and staining intensity are much lower in adjacent non-cancerous tissue (A.×40; B.×200) than in breast cancer (C.×40; D.×200).</p

Expression of XRCC3 and RAD51 in breast cancer and adjacent non-cancerous tissue.

<p>Expression of XRCC3 and RAD51 in breast cancer and adjacent non-cancerous tissue.</p

Multivariate analysis by logistic regression analysis.

<p>Multivariate analysis by logistic regression analysis.</p

Association between XRCC3 and RAD51.

<p>Association between XRCC3 and RAD51.</p

Correlation between expression of XRCC3 and RAD51 and clinicopathological factors.

<p>Correlation between expression of XRCC3 and RAD51 and clinicopathological factors.</p

Image_1_Feasibility of challenging treadmill speed-dependent gait and perturbation-induced balance training in chronic stroke patients with low ambulation ability: a randomized controlled trial.pdf

BackgroundTreadmill training shows advantages in the specificity, amount, and intensity of gait and balance practice for the rehabilitation of stroke patients.ObjectiveTo investigate the feasibility and effectiveness of challenging treadmill speed-dependent gait and perturbation-induced balance training in chronic stroke patients with low ambulation ability.MethodsFor this randomized controlled trial (Chinese Clinical Trials.gov registration number ChiCTR-IOR-16009536) with blinded testers, we recruited 33 ambulatory stroke participants with restricted community ambulation capacity and randomly assigned them into two groups: the experimental group with 2 week treadmill speed-dependent gait training combined with 2 week treadmill perturbation-induced balance training (EXP) or the control group with traditional gait and balance training (CON). Various variables were recorded during EXP training, including the rating of perceived exertion, heart rate, causes of pauses, treadmill speed, and perturbation intensity. Outcome measures were examined before training and at 2 and 4 weeks after training. They included gait velocity during five-meter walk test at comfortable and fast speed and reactive balance ability in the compensatory stepping test as primary outcome measures, as well as dynamic balance ability (timed up-and-go test and 5 times sit-to-stand test) and balance confidence as secondary outcome measures.ResultsAll participants completed the study. The treadmill speed and perturbation intensity significantly increased across training sessions in the EXP group, and no adverse effects occurred. The normal and fast gait velocities showed significant time and group interaction effects. They significantly increased after 2 and 4 weeks of training in the EXP group (p  0.05). Likewise, dynamic balance ability measured using the timed up-and-go test at a fast speed significantly improved after 2 and 4 weeks of training in the EXP group (p  0.05), although without a significant time and group interaction effect. Surprisingly, the reactive balance ability did not show improvement after treatment in the EXP group (p > 0.05).ConclusionChallenging treadmill speed-dependent gait and treadmill perturbation-induced balance training is feasible and effective to improve ambulation function in chronic stroke patients with low ambulation ability.</p

Soil CO₂ concentrations and flux.

<p>Comparison of mean CO₂ concentrations across three depths and flux between and within upland (n = 23) and riparian (n = 9) plots during wet (Weeks 1–3), transition (Weeks 4–6), and dry (Weeks 7–9) periods of the 2013 growing season. Asterisks (*) indicate significant differences between groups (p<0.05, Welch’s ANOVA). Bars indicate standard errors of the mean.</p

Additional file 1: of Aortoesophageal fistula and arch pseudoaneurysm after removing of a swallowed chicken bone: a case report of one-stage hybrid treatment

The procedure of the placement of an occluder combined with aortic stent for pseudoaneurysm. (MP4 82,688 kb

Summer dry-down modulates the isotopic composition of soil CO₂ production in snow-dominated landscapes

<div><p>In mountainous landscapes, soil moisture is highly dynamic due to the effects of topography and the temporal variability imposed by seasonal precipitation, including rainfall and snow. Soil moisture is known to affect ecosystem carbon exchange both aboveground and belowground, as well as the stable isotopic composition of exchanged CO₂. In this study we used an extensive suite of measurements to examine the effects of seasonal changes in soil moisture on the isotopic composition of soil CO₂ production at the landscape level. We show that the seasonal decline in soil moisture (i.e., summer dry-down) appeared to impose a trend in the δ¹³C of soil CO₂ production (δ_P) with more negative δ_P early in the growing season when soils were wet, and more positive δ_P as the growing season progressed and soils dried out. This seemingly generalizable pattern for a snow-dominated watershed is likely to represent the variability of recently assimilated C, tracked through the plant-soil system and imprinted in the respired CO₂. Thus, our observations suggest that, at least for mountainous environments, seasonal changes in δ_P are largely mediated by soil moisture and their spatial variability is partially organized by topography.</p></div

Seasonal soil moisture.

<p>Weekly averaged soil moisture in upland and riparian soil plots during the 2013 growing season.</p